Uveal melanoma

A melanoma that originates from uveal MELANOCYTES and is the most common primary intraocular malignancy. Tumors consist of four cell types: epitheloid, intermediate, mixed, and spindle. Somatic mutations in BAP1, GNAQ, GNA11, EIF1AX, and SF3B1 genes have been identified. OMIM: 155720

Also Known As:

Melanoma of the Uvea; Melanoma, Uveal

Neoplasms: 1361496
- Neoplasms by Site: 4
  - Skin Neoplasms: 9184
    - Melanoma: 72082
      - Uveal melanoma: 2489
  - Eye Neoplasms: 66
    - Uveal Neoplasms
      - Uveal melanoma: 2489
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4514
    - Neuroectodermal Tumors: 216
      - Neuroendocrine Tumors: 6524
        Melanoma: 72082
        Uveal melanoma: 2489
  - Nevi and Melanomas: 63
    - Melanoma: 72082
      - Uveal melanoma: 2489
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 216
      - Neuroendocrine Tumors: 6524
        Melanoma: 72082
        Uveal melanoma: 2489
Skin and Connective Tissue Diseases
- Skin Diseases: 13402
  - Skin Neoplasms: 9184
    - Melanoma: 72082
      - Uveal melanoma: 2489
Eye Diseases: 3620
- Eye Neoplasms: 66
  - Uveal Neoplasms
    - Uveal melanoma: 2489
- Uveal Diseases: 16
  - Uveal Neoplasms
    - Uveal melanoma: 2489

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